I injected a few of the endocannabinoids thought to have recreational potential (dissolved in ethanol, btw- major pain, will never repeat). There is no dose of APAP that will get you high no matter what you do.
I'm guessing it's because it eats through the teeth I wonder what the biggest factor in meth causing tooth loss is...besides poor hygiene while high and the couple days after coming down, I guess it has to do with users smoking and injecting the drug..thoughts?
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Actually, I just learned that acetaminophen is a fatty acid amide hydrolase inhibitor. Actually, I just learned that acetaminophen is a fatty acid amide hydrolase inhibitor. If you follow the link from the acetaminophen page on Wikipedia to the page on AM404 ( that page has references to articles apparently asserting that (1) AM404 is a metabolite of acetaminophen and (2) that AM404 inhibits FAAH...
I've not followed up these references, but they sound like they should corroborate the assertion, maybe?
He’s joined by comedy stars Brian Jordan Alvarez, Tara Di Francisco, Julie Goldman, Stephen Guarino, Ken Kirby, Lyric Lewis, Courtney Pauroso and Bill Posley—along with a special appearance by Superfruit.
Am I right in thinking that one could dramatically increase serum levels of N-arachidonoylethanolamine (anandamide) - anandamide especially but other endocannabinoids as well - by consuming the following readily obtainable substances: Ibuprofen (inhibits cyclooxygenase which converts arachidonic acid into various prostanoids.) Linoleic acid (converted into arachidonic acid) Lecithin (consists of: phosphatidylethanolamine, phosphatidylcholine, phosphatidylinositol, phosphatidic acid) Inositol 5-lipoxygenase inhibitor (Zileuton/Azelastine/Diethylcarbamazine/nordihydroguaiaretic acid) (arachidonate 5-lipoxygenase converts arachidonic acid into leukotrienes) Or do you suppose that fatty acid amide hydrolase is too abundant or too efficient for this combination to have a noticeable psychotropic effect?
Stress can increase endocannabinoids, and so can lowered levels of leptin and elevated calcium.
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